radiation therapy is considered as one of the main methods in cancer treatment. in this method, determination of exact location and geometric properties of tumor is necessary for treatment planning that leads to increased accuracy and output of treatment and reduction of healthy tissue dose. for this purpose, the aim of the present study has been physiological transmission of gallium as a pharm...

purpose: to recognize affective factors in delivering x-ray contrast agents (which have high atomic number) via gallium carrier to liver or lymphatic neoplasm cells.   materials and methods: since uptake of gallium by liver has been reported in numerous researches, it was bonded with a contrast media (metrizoate). x-ray imaging was done to determine geometric features of liver.   results: radio...

The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications. The natural-based plasticizers characterized b...

Drug delivery research areas is continuously broaden and modified as a results of the realization of many factors (such as poor drug solubility and/or absorption, rapid metabolism, high fluctuation in the drug plasma level and variability) adversely affect in-vivo results, in conventional drug delivery system. Lipids are one of the basic building blocks of biological membranes. Nanoscale-based ...

In recent years, there is a lot of interest in synthesis of nanostructures as carriers for drug delivery.These structures are considered as a highly effective drug delivery system due to controlling drugrelease, protecting the pharmaceutical molecule, and environmentally friendly. In this study, thesynthesis of chitosan nanoparticles was carried out by chemical method. The nan...

in this research at the first enalapril drug and its fullerene derivative were optimized. nbo calculations and nmr for the complexes were carried out at the b3lyp/6-31g* quantum chemistry level. different parameters such as energy levels, the amount of chemical shift in different atoms, the amount of homo/lumo, chemical potential (µ ), chemical hardness (η), the coefficients of hybrid bonds (π,...

background: acute poisoning is a major public health problem in bangladesh. it is a common method for suicide. a clear picture regarding clinical presentation, most commonly used toxic agents, background factors and outcome of poisoned patients is necessary in every region. the aim of this study was to investigate frequency and outcome of acute pharmaceutical and chemical poisoning cases in nor...

Background US drug prices are among the highest worldwide as US policy makers have historically been reluctant to embrace price regulations, instead relying on market forces to set prices. However, the introduction of a number of breakthrough, highly effective and high-cost specialty medicines over the past years has stoked the fire of the long-running drug price debate in the USA. The prices o...

The field of drug discovery is ever growing and excipients play a major role in it. A novel class of amphiphiles has been discussed in the review. The review focuses on natural as well as synthetic bolaamphiphiles, their chemical structures and importantly, their ability to self assemble rendering them of great use to pharmaceutical industry. Recent reports on their ability to be used in fabric...